Prof Sarah Tabrizi

Who Prof Sarah Tabrizi is

Professor Sarah Tabrizi CBE FRS FMedSci is Director of the UCL Huntington's Disease Centre, which she co-founded with Professor Gill Bates in 2016, and Joint Head of Department of Neurodegenerative Disease at the UCL Queen Square Institute of Neurology. She is also a Principal Investigator at the UK Dementia Research Institute at UCL and an Honorary Consultant Neurologist at the National Hospital for Neurology and Neurosurgery, Queen Square, where she has led a Huntington's disease multidisciplinary clinical service since 2003. She graduated with a first-class degree in biochemistry from Heriot-Watt University and an MB ChB with the Gold Medal from the University of Edinburgh in 1992, before completing a PhD at UCL in 2000 on mitochondrial dysfunction in neurodegeneration. She has published over 420 peer-reviewed publications and is known for leading the first human trials of nucleic acid therapies in Huntington's disease, including serving as lead scientific advisor on the AMT-130 gene therapy trial that in 2025 reported statistically significant slowing of disease progression. She was appointed CBE in the 2026 King's Birthday Honours for services to people with Huntington's disease.

References for this biography

1. 1.Professor Sarah Tabrizi's Group | UCL Faculty of Brain Sciences — Current roles, co-founding of UCL HD Centre, AMT-130 trial leadership, Nature's 10 recognition, academic career history
2. 2.Professor Sarah Tabrizi | University College London Hospitals NHS Foundation Trust — Clinical roles, NHNN service since 2003, publication count, fellowship elections, career progression
3. 3.Sarah Tabrizi | About | University College London — Academic profile, expert panel memberships, APPG co-founding, awards chronology
4. 4.Prof Sarah Tabrizi | UK DRI — UK DRI Principal Investigator role, publication count (420+), fellowship elections (FRS, FMedSci, NAM), LinkedIn URL
5. 5.UCL staff recognised in King's Birthday Honours | UCL News — CBE awarded in 2026 King's Birthday Honours for services to people with Huntington's disease
6. 6.Professor Sarah Tabrizi elected as Fellow of the Royal Society | UCL Faculty of Brain Sciences — Election as FRS in 2024
7. 7.MRC Millennium Medal for Professor Sarah Tabrizi | UCLH Biomedical Research Centre — MRC Millennium Medal 2022 award
8. 8.UCL scientist named in Nature's Top 10 people who helped shape science in 2025 | UCL Faculty of Brain Sciences — Named in Nature's 10 for 2025; AMT-130 trial results (75% slowing of progression over 36 months)
9. 9.Professor Sarah Tabrizi FMedSci FRS | Royal Society Fellow — Royal Society citation; research contributions and prizes listed
10. 10.Tabrizi Lab | UK DRI — Organisation postcode (WC1N 3BG) and address: UCL Queen Square Institute of Neurology, UCL Huntington's Disease Centre, Queen Square, London

Notable achievements

• Led the early-phase clinical trial of the gene therapy AMT-130, which in September 2025 reported the first statistically significant slowing of Huntington's disease progression in humans, with high-dose treatment associated with a 75% reduction in disease progression over 36 months. Source ↗
• Named in Nature's 10 for 2025 — Nature journal's annual global list of scientists who made the most significant impact that year — recognised as a 'Huntingtons Hero'. Source ↗
• Elected Fellow of the Royal Society in 2024 for pioneering research into disease mechanisms and treatments for Huntington's disease. Source ↗
• Appointed CBE in the 2026 King's Birthday Honours for services to people with Huntington's disease. Source ↗
• Awarded the MRC Millennium Medal for 2022 for outstanding achievements in medical research into neurodegeneration. Source ↗
• Co-founded the UK All-Party Parliamentary Group for Huntington's disease in 2010. Source ↗

Where Prof Sarah Tabrizi has been quoted

1. Huntington’s disease treated successfully for first time in UK gene therapy trialtheguardian.com · 27 Aug 2026

Related media coverage

Recent UK press coverage of their topics — not necessarily citing them directly.

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• An important step forward in ending corridor care - Colin Poolman | Blog | RCN ScotlandRoyal College of Nursing

Contact & links

• Staff pagehttps://profiles.ucl.ac.uk/6907-sarah-tabrizi
• Staff pagehttps://www.uclh.nhs.uk/our-services/find-consultant/professor-sarah-tabrizi
• Staff pagehttps://www.ukdri.ac.uk/team/sarah-tabrizi
• LinkedInhttps://www.linkedin.com/in/sarah-tabrizi-md-phd-fmedsci-frs-9a1744a/published here ↗
• Websitehttps://www.ucl.ac.uk/brain-sciences/ion/research/research-departments/neurodegenerative-disease/people/professor-sarah-tabrizis-group

Organisational contact points only, each taken from a page the organisation publishes itself. No personal or direct contact details are held or shown.