Joann Diray ArceAcademic

Biography

Dr Joann Diray-Arce is an Assistant Professor of Pediatrics at Harvard Medical School and an Affiliate Faculty member at the Broad Institute of MIT and Harvard. She leads the Data Management and Analysis Core (DMAC) within the Precision Vaccines Program (PVP) at Boston Children's Hospital, where she specialises in systems immunology and computational biology. She leads and co-investigates multiple NIH-funded programmes characterising vaccine- and infection-induced immune responses across international and multi-centre consortia. She served as lead of the Clinical and Data Coordinating Center for a landmark NIH-funded Nature study of COVID-19 biomarkers across 1,154 hospitalised patients, which linked dormant-virus reactivation to long COVID. Her work on the Immune Data Resource — a curated compendium of systems vaccinology datasets spanning 53 cohorts and 24 vaccines — has been widely cited in the field of precision vaccine development.

References

1. 1.Joann Arce | Boston Children's Research — Current role, titles, institutional affiliation, Immune Data Resource achievement, and publication list
2. 2.Severe COVID-19 reactivates dormant viruses, study finds | Boston Children's Hospital — Role as lead of Clinical and Data Coordinating Center and PVP-DMAC; quote in press coverage of the IMPACC Nature study
3. 3.Dr Joann Diray Arce on advancing precision vaccines through systems immunology: touchIMMUNOLOGY Future Leaders 2026 — Assistant Professor of Pediatrics title, Broad Institute affiliation, consortium leadership (HIPC, IDEAL, IMPACC, INSIS), Future Leaders 2026 recognition
4. 4.Joann Diray Arce | Vaccine Congress USA — Affiliate Faculty at Broad Institute of MIT and Harvard; expertise in genomics, transcriptomics, proteomics, metabolomics

Expertise

Cited on

• Long Covid

Stated areas of expertise

• Systems immunology
• COVID-19 biomarkers and long COVID
• Vaccine immunogenicity and precision vaccines
• Multi-omics and bioinformatics
• Newborn and early-life immunology
• Clinical and data coordination for large consortia

Notable achievements

• Led the Clinical and Data Coordinating Center for the NIH-funded IMPACC Nature study — the largest COVID-19 biomarker study to date — following 1,154 hospitalised patients and generating over 1 billion data points, with findings linking Anelloviridae reactivation to long COVID. Source ↗
• Led the 'Immune Signatures Data Resource' (Immune Data Resource) under the Human Immunology Project Consortium — a compendium of curated systems vaccinology datasets from 53 cohorts and 24 vaccines, published in Scientific Data (2022). Source ↗
• Named a touchIMMUNOLOGY Future Leader 2026 for her work advancing precision vaccines through systems immunology. Source ↗

What they’ve said

• “This is the largest and most comprehensive biomarker study of COVID-19, in which we followed more than one thousand patients, collected more than 200,000 samples, and generated more than 1 billion data points over the course of a year for this public resource.”

  PhD, leads the PVP-Data Management and Analysis Core and lead of the study's Clinical and Data Coordinating Center · Long Covid · 27 Aug 2026 · COVID-19 awakens dormant viruses — and one is linked to long COVID ↗

• “This is the largest and most comprehensive biomarker study of COVID-19, in which we followed more than one thousand patients, collected more than 200,000 samples, and generated more than one billion data points over the course of a year for this public resource.”

  PhD, lead of the study's Clinical and Data Coordinating Center and leads the PVP-Data Management and Analysis Core · Long Covid · 12 Aug 2026 · COVID-19 Reactivates Dormant Viruses, Offering New Clues to Long COVID ↗

Source references

1. COVID-19 awakens dormant viruses — and one is linked to long COVIDsciencedaily.com · 27 Aug 2026
2. COVID-19 Reactivates Dormant Viruses, Offering New Clues to Long COVIDgenengnews.com · 12 Aug 2026

Contact & links

• Staff pagehttps://research.childrenshospital.org/researchers/joann-arce
• LinkedInhttps://www.linkedin.com/in/joann-diray-arce-phd-79407343/published here ↗
• ORCIDhttps://orcid.org/0000-0003-2183-4269
• Websitehttps://linktr.ee/joanndarce
• Press office emailprecisionvaccinesprogram@childrens.harvard.edupublished here ↗

Organisational contact points only, each taken from a page the organisation publishes itself. No personal or direct contact details are held or shown.